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Translational Neuropharmacology Lab (Zanos Lab)

Translational Neuropharmacology Lab (Zanos Lab)

Our laboratory, based in Cyprus, employs molecular and systems neuroscience, behavioral pharmacology, as well as advanced computational methods to unravel the mysteries of brain diseases and identify targets for the development of novel and effective pharmacotherapies.

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Category: News

News

NEW BIOINFORMATICS MANUSCRIPT: From Viral Infections to Alzheimer’s Disease: Unveiling the Mechanistic Links Through Systems Bioinformatics

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Viruses Might Influence the Development of Alzheimer’s Disease!! Scientists have long been curious about the connection between viral infections and the onset of Alzheimer’s Disease (AD), a debilitating condition characterized by memory loss and cognitive decline. Here, we used a systems bioinformatics approach to explore the potential roles of various viruses, including Herpes Simplex Virus […]

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Dr. Zanos presents our latest findings on novel mechanisms underlying ketamine’s antidepressant action

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The Director of the Translational Neuropharmacology Lab, Dr. Zanos, presented our latest data concerning the potential role of NMDA receptor activation underlying ketamine’s antidepressant mechanism of action. This invited talk was a part of the Hellenic Society for Neuroscience (HSfN) conference. Dr. Zanos’s talk centered on revealing the crucial role of NMDA receptor activation in facilitating […]

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NEW PUBLICATION: Unraveling the transcriptomic signatures of Parkinson’s Disease and Major Depression using single-cell and bulk data

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Curious to know what Parkinson’s disease and Major depression have in common? So are we! Explore our latest publication, where we analyze single-cell and bulk data to unravel their transcriptomic signatures. https://www.frontiersin.org/articles/10.3389/fnagi.2023.1273855/abstract Transnational Neuropharmacology Lab

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Dr. Zanos Delivers Invited Lecture to the General Public: “Understanding the Effects of Drugs of Abuse on the Brain and Discovering Innovative Pharmacotherapies”

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We are excited to announce that Dr. Zanos was invited to deliver a special lecture to the general public, shedding light on the profound impact of drugs of abuse on the brain and presenting innovative pharmacotherapies. In this engaging and informative presentation, Dr. Zanos shared his expertise on the subject, providing valuable insights into the […]

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Current Research Projects

Efficacy of ketamine and its hydroxynorketamine metabolites in substance use disorders Our laboratory is actively investigating the efficacy of ketamine and (2R,6R)-hydroxynorketamine on preventing maladaptive behavioral responses and relapse to opioid-seeking behaviors during protracted abstinence. We use rodent models for studying addictive-like behaviors and in parallel we do establish novel and translationally-valid models to understand […]

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Contact Us

Please fill out the form below with the requested information, and we will get in touch with you shortly Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form. Name * FirstLast Email *Comment or Message Submit     Contact Person: Dr. Panos Zanos Phone: (+357) […]

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Selected Publications

2025 Altas, B., Georgiou, P., Zanos, P., Onisiforou, A. (2025). VirTarget: Virus-Informed Pharmacogenomics Framework Identifies Immunotherapies That Mitigate Epstein–Barr Virus–Driven Dysregulation in Multiple Sclerosis, bioRxiv. https://doi.org/10.1101/2025.11.03.686445.   Onisiforou, A. (2025). VirTrack: A Framework for Inferring Viral Influence on Disease–Associated Transcriptomes — Clinical Type–Specific Epstein–Barr Virus Pathogenesis in Multiple Sclerosis, bioRxiv. https://doi.org/10.1101/2025.10.05.680499.   Georgiou, A., Zanos, […]

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Director of the Translational Neuropharmacology Lab

Dr. Panos Zanos, BSc, Ph.D. Dr. Zanos is a researcher in the field of brain diseases, dedicated to uncovering innovative therapies for major depressive disorders and related brain disease, which present a pressing global health challenge. His groundbreaking research holds the promise of transforming the treatment landscape and making a profound impact on the lives […]

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Current Team Members

Presently, the Zanos lab is comprised of: 1 Senior Researcher 1 Research Associate / Marie Skłodowska-Curie Fellow 5 postdoctoral researchers (including 3 Marie Skłodowska-Curie Fellows) 4 Ph.D. students 4 Research Assistants We invite you to explore the profiles of each of our dedicated members below!   Dr. Anna Onisiforou, BA, BSc, MSc, MSc, Ph.D. Senior […]

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Vacancies

Got a passion for addiction neuroscience, mood disorders, or using advanced systems bioinformatics to decode brain diseases? To express your interest, please fill out the form below. Our team will review your submission, and we will contact you if your profile aligns with any opportunities.  Please enable JavaScript in your browser to complete this form.Please enable […]

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Recent Posts

  • New pre-print: VirTarget framework reveals how Multiple Sclerosis immunotherapies engage with Epstein-Barr Virus-driven disease mechanisms November 6, 2025
  • New preprint: VirTrack framework reveals stage-specific EBV pathogenesis in Multiple Sclerosis October 26, 2025
  • Translational Neuropharmacology Lab presents on novel therapies for brain disorders October 25, 2025
  • Dr. Zanos was invited and presented on antidepressant mechanisms of action of ketamine and other rapid-acting antidepressants at the 6th German-Cypriot Psychotherapy Conference October 7, 2025
  • Featured in Nature Mental Health: Advancing ketamine research and brain pathology treatments October 3, 2025

Navigation

  • Home
  • News
  • Team Members
    • Lab Director
    • Current Team Members
    • Alumni
  • Research
  • Research Units
    • Translational Neuropharmacology Unit
    • Clinical Neuropsychopharmacology Unit
    • AI & Systems Bioinformatics Unit Cyprus
    • Genetic Epidemiology Unit
  • Facilities
  • Publications
  • Media
  • Join Us
  • Contact
  • More

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