Category: News
Dr. Zanos presents new data on ketamine’s mechanisms of action at the European University of Cyprus
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Dr. Zanos presented our latest pre-clinical data on the antidepressant mechanisms of action of ketamine during an invited speech at the European University of Cyprus. Our research provides compelling evidence that indirect activation of NMDA receptors, rather than their inhibition, may be the key mechanism responsible for ketamine’s rapid antidepressant effects. This challenges the conventional […]
New genetic epidemiology paper
Dr. Georgiou, a Marie Curie fellow at the Zanos lab, has published a novel study entitled “Investigating the shared genetic basis and causal relationships between mucosa-associated lymphoid tissue inflammation and psychiatric disorders”. The study employed a two-sample Mendelian randomization analysis using genetic data from over 342,000 FinnGen participants to investigate potential causal relationships between inflammation of […]
Our postdoctoral researcher, Dr. Eleftheria Charalambous presents on her fascinating findings about viruses/bacteria and their association with Alzheimer’s Disease
Our talented postdoctoral researcher, Dr. Eleftheria Charalambous gave a fascinating presentation to peers from the University Medicine Greifswald on her latest findings exploring potential links between viral/bacterial infections and Alzheimer’s disease. Dr. Charalambous’ research focuses on microbe-host interactions, including the gut-brain and oral-brain axes, and how they impact immune function, the hypothalamic-pituitary-adrenal axis, brain aging, […]
The Zanos Lab announces affiliation with the Center for Applied Neuroscience in Cyprus
The Translational Neuropharmacology Lab (Zanos Lab) is announcing its formal affiliation with the Center for Applied Neuroscience (CAN) in Cyprus. This partnership marks an important milestone in our ongoing efforts to advance knowledge in the field of Neuroscience. Becoming a member of CAN, a research center known for pioneering neuroscience research, recognizes the dedicated efforts […]
New research paper – Unravelling the transcriptomic landscape of Alzheimer’s Disease
Our newly published study, led by Dr. Onisiforou and collaborators, unveils importantsex-specific molecular signatures within the hippocampus in Alzheimer’s disease (AD). Through meticulous analysis of postmortem samples, we have uncovered distinct gene expression patterns between male and female AD patients. Notably, our findings shed light on potential gender-specific mechanisms underlying AD susceptibility and progression. This […]
The Zanos lab joins RePo4EU drug repurposing community
The Zanos lab has joined the community of REPO4EU, an industry-level online platform dedicated to validated precision drug repurposing, with a worldwide impact. REPO4EU’s overarching objective is to position this platform as a central data hub, facilitating the exchange of crucial information, providing comprehensive training resources, fostering matchmaking opportunities, and nurturing collaborative initiatives to promote […]
The Zanos lab welcomes our new ONISILOS Marie Sklodowska Curie fellow, Dr. Andrea Georgiou.
Her proposed case-control study (participants that achieved abstinence for at least 6 months after smoking cessation versus participants that did not achieve abstinence) aims to identify novel genetically-supported drug targets for smoking cessation and to correlate/associate changes in those druggable protein targets with: (a) motivation to quit smoking and (b) vulnerability to relapse following abstinence. For […]
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Alumni
Dr. Mary Haddad, BSc, MSc, Ph.D. Postdoctoral, Marie Skłodowska-Curie Fellow Mary will start working in the Zanos lab in June 2024. Dr. Haddad’s research interests revolve around exploring the complex interplay between molecular mechanisms, particularly focusing on the role of soluble epoxide hydrolase (sEH) and its inhibitors in conditions like depression, pain, inflammation, and neurodegenerative […]