Category: News
Our postdoctoral researcher, Dr. Eleftheria Charalambous presents on her fascinating findings about viruses/bacteria and their association with Alzheimer’s Disease
Our talented postdoctoral researcher, Dr. Eleftheria Charalambous gave a fascinating presentation to peers from the University Medicine Greifswald on her latest findings exploring potential links between viral/bacterial infections and Alzheimer’s disease. Dr. Charalambous’ research focuses on microbe-host interactions, including the gut-brain and oral-brain axes, and how they impact immune function, the hypothalamic-pituitary-adrenal axis, brain aging, […]
The Zanos Lab announces affiliation with the Center for Applied Neuroscience in Cyprus
The Translational Neuropharmacology Lab (Zanos Lab) is announcing its formal affiliation with the Center for Applied Neuroscience (CAN) in Cyprus. This partnership marks an important milestone in our ongoing efforts to advance knowledge in the field of Neuroscience. Becoming a member of CAN, a research center known for pioneering neuroscience research, recognizes the dedicated efforts […]
New research paper – Unravelling the transcriptomic landscape of Alzheimer’s Disease
Our newly published study, led by Dr. Onisiforou and collaborators, unveils importantsex-specific molecular signatures within the hippocampus in Alzheimer’s disease (AD). Through meticulous analysis of postmortem samples, we have uncovered distinct gene expression patterns between male and female AD patients. Notably, our findings shed light on potential gender-specific mechanisms underlying AD susceptibility and progression. This […]
The Zanos lab joins RePo4EU drug repurposing community
The Zanos lab has joined the community of REPO4EU, an industry-level online platform dedicated to validated precision drug repurposing, with a worldwide impact. REPO4EU’s overarching objective is to position this platform as a central data hub, facilitating the exchange of crucial information, providing comprehensive training resources, fostering matchmaking opportunities, and nurturing collaborative initiatives to promote […]
The Zanos lab welcomes our new ONISILOS Marie Sklodowska Curie fellow, Dr. Andrea Georgiou.
Her proposed case-control study (participants that achieved abstinence for at least 6 months after smoking cessation versus participants that did not achieve abstinence) aims to identify novel genetically-supported drug targets for smoking cessation and to correlate/associate changes in those druggable protein targets with: (a) motivation to quit smoking and (b) vulnerability to relapse following abstinence. For […]
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Alumni
Dr. Mary Haddad, BSc, MSc, Ph.D. Postdoctoral, Marie Skłodowska-Curie Fellow Mary will start working in the Zanos lab in June 2024. Dr. Haddad’s research interests revolve around exploring the complex interplay between molecular mechanisms, particularly focusing on the role of soluble epoxide hydrolase (sEH) and its inhibitors in conditions like depression, pain, inflammation, and neurodegenerative […]
AI & Systems Bioinformatics Unit Cyprus
AI & Systems Bioinformatics Unit – University of Cyprus: Advancing Bioinformatics research in Cyprus, Europe, and beyond The AI & Systems Bioinformatics Unit, established in 2023 and led by Dr. Anna Onisiforou, is based at the University of Cyprus within the Translational Neuropharmacology Laboratory (Zanos Lab). The unit develops computational approaches that integrate artificial intelligence, […]
OUR NEW PRE-PRINT: (2R,6R)-hydroxynorketamine facilitates extinction and prevents emotional impairment and stress-induced reinstatement in morphine abstinent mice
In the realm of opioid addiction crisis faced by many parts of the world, a significant challenge is the high relapse rates during periods of abstinence, often triggered by stress and negative emotional states. Our findings advance our understanding on opioid addiction neurobiology and treatment options by exploring the therapeutic potential of (2R,6R)-hydroxynorketamine (HNK) in […]