We are thrilled to share that Dr. Panos Zanos was invited to appear on RIK Sat, the satellite television channel of the Cyprus Broadcasting Corporation (CyBC), to discuss the critical issue of drug addiction. This invitation from RIK Sat, one of Cyprus’s premier broadcasting platforms, underscores the significance of Dr. Zanos’ work in the field […]

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We are pleased to announce the release of a new preprint from Dr. Anna Onisiforou and Dr. Panos Zanos, titled “Network-Based Analysis Identifies Targetable Pathways in Comorbid Type II Diabetes and Neuropsychiatric Disorders.” This preprint is available on bioRxiv and represents a significant step forward in understanding the complex interactions between Type 2 Diabetes Mellitus […]

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We are excited to share that Dr. Zanos was invited by OFSEAK Cyprus and the Cyprus Anti-Cancer Society to deliver a keynote address on the neurobiology of drug addiction at a recent Substance Use Disorders Awareness event. This notable event took place in Cyprus and was covered extensively by several television outlets. Dr. Zanos’s presentation […]

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We are excited to announce the latest publication from our talented Research Associate and Head of the Bioinformatics Unit, Dr. Anna Onisiforou, in collaboration with Dr. Polymnia Georgiou. Their groundbreaking paper, titled “Molecular signatures of premature aging in Major Depression and Substance Use Disorders,” has been published in Scientific Data (Nature Group). Major depressive disorder (MDD) and […]

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Her presentation, titled “The gut phageome is associated with healthy brain ageing” drew significant interest from fellow researchers. Dr. Charalambous’s work explores the connection between bacteriophages in the gut microbiome and cognitive health as we age. Her research suggests that the makeup and variety of the gut phageome may play an important role in maintaining […]

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Dr. Zanos was recently invited to speak on a TV channel about the neurobiology of alcohol addiction, where he explored the complex processes that lead from casual alcohol use to full-blown dependence. Initially, alcohol consumption often presents an aversive taste; however, this negative experience is quickly overshadowed by the activation of the brain’s reward system. […]

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Our latest book chapter delves into the complex interactions between the central nervous system and endocrine signals, highlighting their crucial role in shaping emotional processing and behaviors related to anxiety. While the hypothalamic-pituitary-adrenal (HPA) axis has traditionally been the focal point, this chapter expands the discussion to include various steroid and peptide hormones that are […]

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Dr. Zanos recently presented our latest research on the antidepressant actions of ketamine and other potential antidepressants at the European University of Cyprus. His talk focused on the role of NMDA receptor (NMDAR) activation in the rapid antidepressant effects of these compounds. Contrary to the traditional view of ketamine as an NMDAR antagonist, our findings […]

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Dr. Zanos presented our latest pre-clinical data on the antidepressant mechanisms of action of ketamine during an invited speech at the European University of Cyprus. Our research provides compelling evidence that indirect activation of NMDA receptors, rather than their inhibition, may be the key mechanism responsible for ketamine’s rapid antidepressant effects. This challenges the conventional […]

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Dr. Georgiou, a Marie Curie fellow at the Zanos lab, has published a novel study entitled “Investigating the shared genetic basis and causal relationships between mucosa-associated lymphoid tissue inflammation and psychiatric disorders”. The study employed a two-sample Mendelian randomization analysis using genetic data from over 342,000 FinnGen participants to investigate potential causal relationships between inflammation of […]

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