Category: News
AI & Systems Bioinformatics Unit Cyprus
AI & Systems Bioinformatics Unit – University of Cyprus: Advancing Bioinformatics research in Cyprus, Europe, and beyond The AI & Systems Bioinformatics Unit, established in 2023 and led by Dr. Anna Onisiforou, is based at the University of Cyprus within the Translational Neuropharmacology Laboratory (Zanos Lab). The unit develops computational approaches that integrate artificial intelligence, […]
OUR NEW PRE-PRINT: (2R,6R)-hydroxynorketamine facilitates extinction and prevents emotional impairment and stress-induced reinstatement in morphine abstinent mice
In the realm of opioid addiction crisis faced by many parts of the world, a significant challenge is the high relapse rates during periods of abstinence, often triggered by stress and negative emotional states. Our findings advance our understanding on opioid addiction neurobiology and treatment options by exploring the therapeutic potential of (2R,6R)-hydroxynorketamine (HNK) in […]
NEW BIOINFORMATICS MANUSCRIPT: From Viral Infections to Alzheimer’s Disease: Unveiling the Mechanistic Links Through Systems Bioinformatics
Viruses Might Influence the Development of Alzheimer’s Disease!! Scientists have long been curious about the connection between viral infections and the onset of Alzheimer’s Disease (AD), a debilitating condition characterized by memory loss and cognitive decline. Here, we used a systems bioinformatics approach to explore the potential roles of various viruses, including Herpes Simplex Virus […]
Dr. Zanos presents our latest findings on novel mechanisms underlying ketamine’s antidepressant action
The Director of the Translational Neuropharmacology Lab, Dr. Zanos, presented our latest data concerning the potential role of NMDA receptor activation underlying ketamine’s antidepressant mechanism of action. This invited talk was a part of the Hellenic Society for Neuroscience (HSfN) conference. Dr. Zanos’s talk centered on revealing the crucial role of NMDA receptor activation in facilitating […]
NEW PUBLICATION: Unraveling the transcriptomic signatures of Parkinson’s Disease and Major Depression using single-cell and bulk data
Curious to know what Parkinson’s disease and Major depression have in common? So are we! Explore our latest publication, where we analyze single-cell and bulk data to unravel their transcriptomic signatures. https://www.frontiersin.org/articles/10.3389/fnagi.2023.1273855/abstract Transnational Neuropharmacology Lab
Dr. Zanos Delivers Invited Lecture to the General Public: “Understanding the Effects of Drugs of Abuse on the Brain and Discovering Innovative Pharmacotherapies”
We are excited to announce that Dr. Zanos was invited to deliver a special lecture to the general public, shedding light on the profound impact of drugs of abuse on the brain and presenting innovative pharmacotherapies. In this engaging and informative presentation, Dr. Zanos shared his expertise on the subject, providing valuable insights into the […]
Current Research Projects
Dissecting pollutant exposure and its contribution to neurodegeneration: from signatures to prevention strategies (EXPOSIGNALZ HOP-ON) Our laboratory will investigate causal relationships between pollutant exposure and brain circuit function using systems neuroscience approaches in mouse models. We will examine how exposure to environmentally relevant toxicants with neurotoxic and pro-amyloidogenic properties affects key memory circuits, with particular […]
Contact Us
Please fill out the form below with the requested information, and we will get in touch with you shortly Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form. Name * FirstLast Email *Comment or Message Submit Contact Person: Dr. Panos Zanos Phone: (+357) […]
Selected Publications
2026 Georgiou, P., Altas, B., Onisiforou, M., Zanos, P., Onisiforou, A. (2026). From Heatwaves to Brainwaves: Climate-Driven Microplastics Promote Epstein–Barr Virus Reactivation and Female-Biased Risk for Alzheimer’s Disease and Multiple Sclerosis, Research Square (pre-print). https://doi.org/10.21203/rs.3.rs-8928857/v1. Michael, A., Onisiforou, A., Georgiou, P., Koumas, M., Powels, C., Mammadov, E., Georgiou A.N., Zanos, P. (2026). Justifying and […]
Director of the Translational Neuropharmacology Lab
Dr. Panos Zanos, BSc, Ph.D. Dr. Zanos is a neuroscientist dedicated to uncovering innovative therapies for major depressive disorders and related brain diseases, which present a pressing global health challenge. His groundbreaking research holds the promise of transforming the treatment landscape and making a profound impact on the lives of millions suffering from depression and […]