Category: News
The Zanos lab welcomes our new ONISILOS Marie Sklodowska Curie fellow, Dr. Andrea Georgiou.
Her proposed case-control study (participants that achieved abstinence for at least 6 months after smoking cessation versus participants that did not achieve abstinence) aims to identify novel genetically-supported drug targets for smoking cessation and to correlate/associate changes in those druggable protein targets with: (a) motivation to quit smoking and (b) vulnerability to relapse following abstinence. For […]
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Alumni
Dr. Mary Haddad, BSc, MSc, Ph.D. Postdoctoral, Marie Skłodowska-Curie Fellow Mary will start working in the Zanos lab in June 2024. Dr. Haddad’s research interests revolve around exploring the complex interplay between molecular mechanisms, particularly focusing on the role of soluble epoxide hydrolase (sEH) and its inhibitors in conditions like depression, pain, inflammation, and neurodegenerative […]
AI & Systems Bioinformatics Unit Cyprus
AI & Systems Bioinformatics Unit – University of Cyprus: Advancing Bioinformatics research in Cyprus, Europe, and beyond The AI & Systems Bioinformatics Unit, established in 2023 and led by Dr. Anna Onisiforou, is based at the University of Cyprus within the Translational Neuropharmacology Laboratory (Zanos Lab). The unit develops computational approaches that integrate artificial intelligence, […]
OUR NEW PRE-PRINT: (2R,6R)-hydroxynorketamine facilitates extinction and prevents emotional impairment and stress-induced reinstatement in morphine abstinent mice
In the realm of opioid addiction crisis faced by many parts of the world, a significant challenge is the high relapse rates during periods of abstinence, often triggered by stress and negative emotional states. Our findings advance our understanding on opioid addiction neurobiology and treatment options by exploring the therapeutic potential of (2R,6R)-hydroxynorketamine (HNK) in […]
NEW BIOINFORMATICS MANUSCRIPT: From Viral Infections to Alzheimer’s Disease: Unveiling the Mechanistic Links Through Systems Bioinformatics
Viruses Might Influence the Development of Alzheimer’s Disease!! Scientists have long been curious about the connection between viral infections and the onset of Alzheimer’s Disease (AD), a debilitating condition characterized by memory loss and cognitive decline. Here, we used a systems bioinformatics approach to explore the potential roles of various viruses, including Herpes Simplex Virus […]
Dr. Zanos presents our latest findings on novel mechanisms underlying ketamine’s antidepressant action
The Director of the Translational Neuropharmacology Lab, Dr. Zanos, presented our latest data concerning the potential role of NMDA receptor activation underlying ketamine’s antidepressant mechanism of action. This invited talk was a part of the Hellenic Society for Neuroscience (HSfN) conference. Dr. Zanos’s talk centered on revealing the crucial role of NMDA receptor activation in facilitating […]
NEW PUBLICATION: Unraveling the transcriptomic signatures of Parkinson’s Disease and Major Depression using single-cell and bulk data
Curious to know what Parkinson’s disease and Major depression have in common? So are we! Explore our latest publication, where we analyze single-cell and bulk data to unravel their transcriptomic signatures. https://www.frontiersin.org/articles/10.3389/fnagi.2023.1273855/abstract Transnational Neuropharmacology Lab
Dr. Zanos Delivers Invited Lecture to the General Public: “Understanding the Effects of Drugs of Abuse on the Brain and Discovering Innovative Pharmacotherapies”
We are excited to announce that Dr. Zanos was invited to deliver a special lecture to the general public, shedding light on the profound impact of drugs of abuse on the brain and presenting innovative pharmacotherapies. In this engaging and informative presentation, Dr. Zanos shared his expertise on the subject, providing valuable insights into the […]