Our latest book chapter delves into the complex interactions between the central nervous system and endocrine signals, highlighting their crucial role in shaping emotional processing and behaviors related to anxiety. While the hypothalamic-pituitary-adrenal (HPA) axis has traditionally been the focal point, this chapter expands the discussion to include various steroid and peptide hormones that are increasingly recognized for their impact on anxiety behaviors.

This comprehensive review explores recent advancements in understanding how different hormones, including those associated with brain stress systems, neuropeptides, neurosteroids, and steroid hormones, contribute to anxiety regulation. Insights from both fundamental research and clinical investigations suggest that these hormonal systems may underlie stress-induced changes in anxiety and related behaviors. By exploring these diverse mechanisms, the chapter aims to open new avenues for innovative approaches to treat stress-related mental health conditions.

The chapter identifies a range of neuroendocrine targets, offering a deeper understanding of the mechanisms underlying anxiety disorders and highlighting potential new therapeutic targets. This broadened perspective could lead to more effective strategies for mitigating anxiety and improving mental health outcomes.

For more details check: https://link.springer.com/chapter/10.1007/978-3-031-56798-8_3