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Translational Neuropharmacology Lab (Zanos Lab)

Translational Neuropharmacology Lab (Zanos Lab)

Our laboratory, based in Cyprus, employs molecular and systems neuroscience, behavioral pharmacology, as well as advanced computational methods to unravel the mysteries of brain diseases and identify targets for the development of novel and effective pharmacotherapies.

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Zanos Lab research decodes molecular pathways in Opioid Use Disorder and Depression at Hellenic Psychological Society conference

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Dr. Zanos has presented new research of our lab at the Hellenic Psychological Society (ΕΛΨΕ) conference in Ioannina, Greece. The presentation, titled “Decoding common molecular pathways affected in opioid use disorder and depression,” explored the complex relationship between these frequently co-occurring conditions. This research was led by our lab members, Drs. Anna Onisiforou and Andrea […]

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Our postdoctoral fellow, Dr. Andria Michael, presents at YUFE4Postdocs workshop in University of Antwerp

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We are pleased to announce that our postdoctoral researcher, Dr. Andria Michael, recently participated in the YUFE4Postdocs training workshop hosted at the University of Antwerp. The workshop focused on stakeholder interaction and open science practices, bringing together talented postdoctoral researchers from across the YUFE alliance. During this spring workshop, Dr. Michael had the opportunity to […]

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Zanos Lab postdoctoral researcher Dr. Polymnia Louka contributes expert article on depression and bone health

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We are pleased to announce that Dr. Polymnia Louka of the Zanos Laboratory recently authored an informative article in a prominent Cypriot newspaper addressing the important relationship between depression and bone health. In her article, Dr. Louka explains that depression is one of the most common psychiatric disorders in the modern world, affecting approximately 5% […]

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Zanos Lab Awarded $100,000 IDSA Foundation Grant for Alzheimer’s Research

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We are pleased to announce that Dr. Anna Onisiforou and Dr. Zanos  have been awarded a $100,000 grant from the Infectious Diseases Society of America (IDSA) Foundation. The grant will support an innovative project entitled “Sex-Specific Mechanisms of HSV-1 and EBV in Alzheimer’s Disease Risk.” This competitive funding was awarded through the 2025 Microbial Pathogenesis […]

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Cyprus Neuroscience Society now officially established: A historic milestone for Cyprus’ neuroscience community led by Dr. Zanos

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The Translational Neuropharmacology Lab is proud to announce that the Cyprus Neuroscience Society (C.N.S.), founded and presided over by our Principal Investigator Dr. Panos Zanos, has reached another significant milestone with the launch of its official website: cnscyprus.com. This achievement builds upon Dr. Zanos’s vision to establish the first-ever neuroscience society in Cyprus (Registration Number: […]

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Dr. Zanos discusses innovative ketamine research at the American College of Greece (Deeree) faculty seminar

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On Tuesday, April 8th, Dr. Zanos, Head of the Translational Neuropharmacology Lab, presented his groundbreaking research on ketamine’s antidepressant properties to faculty and students at Deree. The seminar, held in the Faculty Lounge, provided an intimate setting for in-depth discussion of novel therapeutic approaches to depression treatment. Dr. Zanos’s presentation explored the molecular pathways through […]

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New study by the Bioinformatics Unit of the Zanos lab suggests Metformin may offer better Alzheimer’s prevention potential in Diabetes patients compared with Semaglutide

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The Zanos lab has recently published a preprint study examining the comparative effectiveness of diabetes medications in potentially reducing Alzheimer’s disease risk. The research was led by senior researchers Dr. Andrea Georgiou and Dr. Anna Onisiforou, key members of the Zanos laboratory team. The study, titled “Metformin Shows Greater Potential Than Semaglutide in Reducing Alzheimer’s […]

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Dr. Zanos presents our latest findings at University of Athens Neuroscience Seminar Series

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Dr. Zanos, the Head of the Translational Neuropharmacology Lab, had the honor of presenting his research at the University of Athens as part of their Neuroscience Seminar Series. In his talk titled “Decoding ketamine: Neurobiological mechanisms underlying its rapid antidepressant efficacy,” Dr. Zanos shared his team’s findings on ketamine’s unique properties as an antidepressant. He […]

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New Publication: (2R,6R)-hydroxynorketamine prevents opioid abstinence-related negative affect and stress-induced reinstatement

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The Zanos lab has just published a new study in the British Journal of Pharmacology demonstrating that the biologically-active metabolite of ketamine, (2R,6R)-hydroxynorketamine (HNK) shows potential for possibly addressing multiple aspects of opioid use disorder. In this comprehensive investigation, we established several mouse models that mimic some of the human endophenotypes of opioid dependence and […]

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Upcoming Seminar: “Decoding ketamine: Neurobiological mechanisms underlying its rapid antidepressant efficacy”

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We are pleased to announce an upcoming seminar by Dr. Zanos, the Director of the Translational Neuropharmacology Lab at the Center for Applied Neuroscience & Department of Psychology of the University of Cyprus. In this seminar, Dr. Zanos will discuss how unlike traditional monoamine-based antidepressants that require weeks to exert effects, ketamine alleviates depression within […]

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Recent Posts

  • New Publication in Neuroscience & Biobehavioral Reviews: A Hierarchical Framework for Nociplastic Pain September 11, 2026
  • Dr. Charalambous presents brain aging research at AAIC 2026 July 13, 2026
  • Mapping the Epstein-Barr Virus-Multiple Sclerosis Axis: Dr. Anna Onisiforou presents VirTrack and VirTarget at the FENS Forum 2026 July 9, 2026
  • Dr. Panoutsopoulos presents research on ketamine and early neurodevelopment at FENS Forum 2026 July 8, 2026
  • Research spotlight: Unraveling the role of Eukaryotic Elongation Factor 2 Kinase in the antidepressant mechanism of (2R,6R)-hydroxynorketamine June 4, 2026

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  • Team Members
    • Lab Director
    • Current Team Members
    • Alumni
  • Research
  • Research Units
    • Translational Neuropharmacology Unit
    • Clinical Neuropsychopharmacology Unit
    • AI & Systems Bioinformatics Unit Cyprus
    • Genetic Epidemiology Unit
  • Facilities
  • Publications
  • Media
  • Join Us
  • Contact
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