We are excited to announce that Dr. Polymnia Louka, our new postdoctoral researcher, has successfully secured €150,000 in funding through the European Marie-Curie Co-Fund. The grant will support her research project titled “Identifying the Effects of Ketamine and Its Metabolites on Depression-Induced Impairment in Bone Health.” Dr. Louka’s project aims to address a critical gap […]

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We are excited to announce the publication of our latest research in the Computational & Structural Biotechnology Journal, titled “One Path, Two Solutions: Network-Based Analysis Identifies Targetable Pathways for the Treatment of Comorbid Type II Diabetes and Neuropsychiatric Disorders.” This study introduces a novel computational algorithm that provides unprecedented insight into the shared molecular mechanisms […]

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We are thrilled to announce that the Zanos Lab has been awarded a grant to investigate the cellular and molecular mechanisms behind the antidepressant actions of (2R,6R)-hydroxynorketamine ((2R,6R)-HNK), in collaboration with Prof. Kobi Rosenblum. This metabolite of ketamine has shown promise in inducing rapid antidepressant effects without the adverse effects associated with ketamine itself in […]

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We are excited to announce that Dr. Zanos recently presented at the prestigious mGlu 2024 meeting in Sicily, Italy. His talk, titled “Interplay between the mGluR2 signalling and ketamine’s rapid antidepressant actions: Exploring the possible role of NMDAR activation,” offered key insights into the mechanisms underlying ketamine’s antidepressant effects. Stay tuned for more research updates […]

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We are excited to share that Zanos Lab participated in this year’s European Research Night (ERN) event in Cyprus, an initiative aimed at bringing research and innovation closer to the public. During the event, we had the opportunity to engage with students and visitors, offering insights into our ongoing research projects focused on addiction. Our […]

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We are thrilled to announce that our postdoctoral fellow, Dr. Andria Michael, from the Zanos lab, has been awarded a prestigious Marie Skłodowska-Curie young investigator grant under the ONISILOS co-fund scheme. This grant will support Dr. Michael’s innovative research aimed at identifying the role of Vascular Endothelial Growth Factor A (VEGF-A) in the development of […]

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The Zanos lab is excited to announce the publication of our latest research paper in the prestigious journal Biological Psychiatry. Our study explores the potential of ketamine and its metabolites as novel therapeutic strategies for treating Opioid Use Disorder (OUD). In this comprehensive review, we examine both preclinical and clinical research on ketamine’s potential in […]

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The Bioinformatics Unit of the Zanos Lab is proud to announce our latest publication, “From Viral Infections to Alzheimer’s Disease: Unveiling the Mechanistic Links Through Systems Bioinformatics,” which explores the complex relationship between viral infections and Alzheimer’s disease (AD). Dr. Anna Onisiforou utilized advanced systems bioinformatics techniques to investigate how various viruses, including herpesviruses, hepatitis […]

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We are thrilled to announce that our postdoctoral fellow, Dr. Panutsopulos, has been awarded a Marie Skłodowska-Curie Young Investigator grant under the ONISILOS co-fund scheme. This grant  will support Dr. Panoutsopoulos’ cutting-edge research aimed at investigating the role of antidepressants, such as SSRIs and ketamine, in the development of neural tube defects (NTDs) during early […]

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We are excited to announce that the Zanos Lab has just been awarded a grant of €20,000 by the A.G. Leventis Foundation. This funding will significantly enhance our ongoing research efforts to uncover the mechanisms of action behind rapid-acting antidepressant compounds. Depression remains one of the most challenging mental health conditions, and the discovery of […]

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