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Translational Neuropharmacology Lab (Zanos Lab)

Translational Neuropharmacology Lab (Zanos Lab)

Our laboratory, based in Cyprus, employs molecular and systems neuroscience, behavioral pharmacology, as well as advanced computational methods to unravel the mysteries of brain diseases and identify targets for the development of novel and effective pharmacotherapies.

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Ms. Despina Melanthiou

Despina Melanthiou, BSc

Ph.D. Student

Despina holds a B.Sc. in Psychology from the University of Cyprus in Nicosia, Cyprus, and is currently a Ph.D. student in Clinical Psychology at the University of Cyprus, also located in Nicosia, Cyprus.

Her research in the Zanos lab focuses on identifying physiological biomarkers of misophonia including elevated cortisol and alpha-amylase in saliva samples, along with distinctive EEG patterns showing hyperactivation in auditory and limbic regions during trigger exposure. Through combining neurophysiological measurements with behavioral assessments, her work provides objective markers for understanding how specific sounds trigger intense emotional and physical reactions. This research serves as a valuable model for studying broader sensory processing dysfunctions and is informing the development of targeted therapeutic interventions. Her integration of neurophysiological data with behavioral outcomes is advancing our understanding of sensory-emotional integration mechanisms.

Research Interests: As a psychologist, Despina’s research interests are centered on improving the quality of life for individuals struggling with psychological disorders. Her research focuses on assessing current therapies and discovering the most effective treatments for patients.

Selected Publications:

  • Konstantinou, P., Ioannou, M., Melanthiou, D., Georgiou, K., Almas, I., Gloster, A. T., … & Karekla, M. (2023). The impact of acceptance and commitment therapy (ACT) on quality of life and symptom improvement among chronic health conditions: A systematic review and meta-analysis. Journal of Contextual Behavioral Science. https://doi.org/10.1016/j.jcbs.2023.08.004.

Contact Info:

Email: melanthiou.despina@ucy.ac.cy

Recent Posts

  • New pre-print: VirTarget framework reveals how Multiple Sclerosis immunotherapies engage with Epstein-Barr Virus-driven disease mechanisms November 6, 2025
  • New preprint: VirTrack framework reveals stage-specific EBV pathogenesis in Multiple Sclerosis October 26, 2025
  • Translational Neuropharmacology Lab presents on novel therapies for brain disorders October 25, 2025
  • Dr. Zanos was invited and presented on antidepressant mechanisms of action of ketamine and other rapid-acting antidepressants at the 6th German-Cypriot Psychotherapy Conference October 7, 2025
  • Featured in Nature Mental Health: Advancing ketamine research and brain pathology treatments October 3, 2025

Navigation

  • Home
  • News
  • Team Members
    • Lab Director
    • Current Team Members
    • Alumni
  • Research
  • Research Units
    • Translational Neuropharmacology Unit
    • Clinical Neuropsychopharmacology Unit
    • AI & Systems Bioinformatics Unit Cyprus
    • Genetic Epidemiology Unit
  • Facilities
  • Publications
  • Media
  • Join Us
  • Contact
  • More

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