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Translational Neuropharmacology Lab (Zanos Lab)

Translational Neuropharmacology Lab (Zanos Lab)

Our laboratory, based in Cyprus, employs molecular and systems neuroscience, behavioral pharmacology, as well as advanced computational methods to unravel the mysteries of brain diseases and identify targets for the development of novel and effective pharmacotherapies.

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Ms. Despina Melanthiou

Despina Melanthiou, BSc

Ph.D. Student

Despina holds a B.Sc. in Psychology from the University of Cyprus in Nicosia, Cyprus, and is currently a Ph.D. student in Clinical Psychology at the University of Cyprus, also located in Nicosia, Cyprus.

Her research in the Zanos lab focuses on identifying physiological biomarkers of misophonia including elevated cortisol and alpha-amylase in saliva samples, along with distinctive EEG patterns showing hyperactivation in auditory and limbic regions during trigger exposure. Through combining neurophysiological measurements with behavioral assessments, her work provides objective markers for understanding how specific sounds trigger intense emotional and physical reactions. This research serves as a valuable model for studying broader sensory processing dysfunctions and is informing the development of targeted therapeutic interventions. Her integration of neurophysiological data with behavioral outcomes is advancing our understanding of sensory-emotional integration mechanisms.

Research Interests: As a psychologist, Despina’s research interests are centered on improving the quality of life for individuals struggling with psychological disorders. Her research focuses on assessing current therapies and discovering the most effective treatments for patients.

Selected Publications:

  • Melanthiou, D., Panayiotou, G., Paraskevopoulos, E., Chatzittofis, A., Koumas, M., Onisiforou, A., Zanos, P (2026). Linking misophonia and tinnitus: Common and divergent neurobiological mechanisms, Neuroscience and Biobehavioral Reviews. https://doi.org/10.1016/j.neubiorev.2026.106584.
  • Konstantinou, P., Ioannou, M., Melanthiou, D., Georgiou, K., Almas, I., Gloster, A. T., … & Karekla, M. (2023). The impact of acceptance and commitment therapy (ACT) on quality of life and symptom improvement among chronic health conditions: A systematic review and meta-analysis. Journal of Contextual Behavioral Science. https://doi.org/10.1016/j.jcbs.2023.08.004.

Contact Info:

Email: melanthiou.despina@ucy.ac.cy

Recent Posts

  • New manuscript: The Immunosuppression Paradox in Multiple Sclerosis: Are We Fueling the Fire by Suppressing Immunity in an Epstein–Barr Virus–Linked Disease? March 12, 2026
  • New Preprint article – From Heatwaves to Brainwaves: Climate-Driven Microplastics Promote Epstein–Barr Virus Reactivation and Female-Biased Risk for Alzheimer’s Disease and Multiple Sclerosis February 24, 2026
  • New Publication – Linking Misophonia and Tinnitus: Common and Divergent Neurobiological Mechanisms January 29, 2026
  • Dr. Zanos Appointed to the Editorial Board of the Neuropharmacology Journal January 17, 2026
  • Zanos lab publishes a short review article on Major Depressive Disorder in Trends in Molecular Medicine January 4, 2026

Navigation

  • Home
  • News
  • Team Members
    • Lab Director
    • Current Team Members
    • Alumni
  • Research
  • Research Units
    • Translational Neuropharmacology Unit
    • Clinical Neuropsychopharmacology Unit
    • AI & Systems Bioinformatics Unit Cyprus
    • Genetic Epidemiology Unit
  • Facilities
  • Publications
  • Media
  • Join Us
  • Contact
  • More

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